ICSI Center

LABORATORY OF ADVANCED REPRODUCTIVE BIOLOGY AND GENETICS

We are dedicated to implementing cutting-edge research in the field of Reproductive Biology. Our primary emphasis lies in exploring the complexities of human gametes–spermatozoa and oocytes–to gain insights into their maturation processes and interactions. Beyond that, our investigation extends to understanding the genetic underpinnings of infertility, employing advanced CRISPR-Cas9 editing techniques.

A significant hallmark of our laboratory is our pioneering success in devising and implementing a groundbreaking gender selection method for spermatozoa prior to Intrauterine Insemination (IUI) and Intracytoplasmic Sperm Injection (ICSI).

American Society for Reproductive Medicine Annual Meeting 2016

DNA Fragmentation in Relation to Sperm Source and Reproductive Outcome

Theodore Paniza, Tyler Cozzubbo, Stephanie Cheung, Alessandra Parrella, Marc Goldstein, Zev Rosenwaks, and Gianpiero D. Palermo

Combined GnRH-Agonist and Human Chorionic Gonadotropin Trigger Enhances Ooplasmic Maturity and Improves ICSI Cycle Outcomes in Patients with Poor Fertilization

Rony T. Elias, M.D., Nigel Pereira, M.D., Tyler Cozzubbo, B.S., Lisa Artusa, B.S.N., Rachel S. Gerber, M.D., Gianpiero D. Palermo, M.D., Ph.D., Zev Rosenwaks, M.D.

Role of Sperm Cell Specific RNA to Screen for Unexplained Male Infertility

Tyler Cozzubbo, Nigel Pereira, Arthur P. Clement, Stephanie Cheung, Zev Rosenwaks, and Gianpiero D. Palermo

Revisiting Oolemma Characteristics by Analyzing Abnormal Fertilization Patterns After Intracytoplasmic Sperm Injection

Nigel Pereira, M.D., Tyler Cozzubbo, B.S., Stephanie Cheung, B.S., Zev Rosenwaks, M.D., Gianpiero D. Palermo, M.D., Ph.D.

Sperm DNA Fragmentation as Treatment Guidance for Infertile Couples

Theodore Paniza, Tyler Cozzubbo, Alessandra Parrella, Stephanie Cheung, Marc Goldstein, Zev Rosenwaks, Gianpiero D. Palermo

RNA-Sequencing to Assess Embryonic Developmental Competence of the Male Gamete

Tyler Cozzubbo, Nigel Pereira, Stephanie Cheung, Zev Rosenwaks, Gianpiero D. Palermo

Aneuploidy Screening and Genome Profiling in Infertile Couples

Stephanie Cheung, Tyler Cozzubbo, Zev Rosenwaks, Gianpiero D. Palermo

Chromosomal Assessment by Next Generation Sequencing on the Male Gamete of Infertile Couples

Stephanie Cheung, Tyler Cozzubbo, Stephen Chow, Zev Rosenwaks, and Gianpiero D. Palermo

Noncoding RNA Profiling as an Indicator of Male Gamete Reproductive Potential

Tyler Cozzubbo, Nigel Pereira, Stephanie Cheung, Arthur P. Clement, Zev Rosenwaks, Gianpiero D. Palermo