ICSI Center

LABORATORY OF ADVANCED REPRODUCTIVE BIOLOGY AND GENETICS

We are dedicated to implementing cutting-edge research in the field of Reproductive Biology. Our primary emphasis lies in exploring the complexities of human gametes–spermatozoa and oocytes–to gain insights into their maturation processes and interactions. Beyond that, our investigation extends to understanding the genetic underpinnings of infertility, employing advanced CRISPR-Cas9 editing techniques.

A significant hallmark of our laboratory is our pioneering success in devising and implementing a groundbreaking gender selection method for spermatozoa prior to Intrauterine Insemination (IUI) and Intracytoplasmic Sperm Injection (ICSI).

European Society of Human Reproduction and Embryology Annual Meeting 2022

ICSI: From Vintage to AI

Olena M. Kocur, Stephanie Cheung, Philip Xie, Zee Rosenwaks, Gianpiero D. Palermo

Evaluating the Reproductive Potential of Azoospermic Men by Profiling the Genome of Surgically Retrieved Spermatozoa

Pak Chung, Stephanie Cheung, Zev Rosenwaks, Gianpiero D. Palermo

Browsing the Male Genome to Unravel Its Reproductive Potential

Stephanie Cheung, Zev Rosenwaks, Gianpiero D. Palermo

Embryo developmental competence of de novo male gametes in a novel three-dimensional culture

Mary McKnight, Philip Xie, Zev Rosenwaks, Gianpiero D. Palermo

Defining the exclusive role of male genome integrity on conceptus development

Lily Ng, Olena Kocur, Philip Xie, Carina Sung, Sydney Souness, Zev Rosenwaks, Gianpiero D. Palermo

Epigenetic Profiling of Seminal Plasma in NOA Men to Predict Successful Testicular Sperm Retrieval

Carina Sung, Philip Xie, Stephanie Cheung, Zev Rosenwaks, Gianpiero D. Palermo